Publications

66. Angewandte Chemie International Edition, 2023, 62, e202303167.

Experimental Confirmation of a Predicted Porous Hydrogen‐Bonded Organic Framework

Caitlin E Shields, Xue Wang, Thomas Fellowes, Rob Clowes, Linjiang Chen, Graeme M Day, Anna G Slater, John W Ward, Marc A. Little*, and Andrew I Cooper

65. Chemical Communications, 2023, 59, 3731-3734.

Competitive Aminal Formation During the Synthesis of a Highly Soluble, Isopropyl-decorated Imine Porous Organic Cage

Rachel J. Kearsey, Andrew Tarzia, Marc A. Little, Michael C. Brand, Rob Clowes, Kim E. Jelfs, Andrew I. Cooper, and Rebecca L. Greenaway 

64. Angewandte Chemie International Edition, 2022,61, e202202450.

Hydrogen Isotope Separation Using a Metal-Organic Cage Built from Macrocycles

Donglin He, Linda Zhang, Tao Liu, Rob Clowes, Marc A. Little*, Ming Liu, Michael Hirscher, and Andrew I. Cooper

63. Journal of the American Chemical Society, 2022, 144, 9893–9901.

Analogy Powered by Prediction and Structural Invariants: Computationally Led Discovery of a Mesoporous Hydrogen-Bonded Organic Cage Crystal

Qiang Zhu, Jay Johal, Daniel E. Widdowson, Zhongfu Pang, Boyu Li, Christopher M. Kane, Vitaliy Kurlin, Graeme M. Day, Marc A. Little*, and Andrew I. Cooper

62. Nature, 2022, 604, 72–79.

Reconstructed Covalent Organic Frameworks

Weiwei Zhang, Linjiang Chen, Sheng Dai, Chengxi Zhao, Cheng Ma, Lei Wei, Minghui Zhu, Samantha Y. Chong, Haofan Yang, Lunjie Liu, Yang Bai, Miaojie Yu, Yongjie Xu, Xiao-Wei Zhu, Qiang Zhu, Shuhao An, Reiner Sebastian Sprick, Marc A. Little, Xiaofeng Wu, Shan Jiang, Yongzhen Wu, Yue-Biao Zhang, He Tian, Wei-Hong Zhu and Andrew I. Cooper

A Smart and Responsive Crystalline Porous Organic Cage Membrane with Switchable Pore Apertures for Graded Molecular Sieving

Ai He, Zhiwei Jiang, Yue Wu, Hadeel Hussain, Jonathan Rawle, Michael E. Briggs, Marc A. Little, Andrew G. Livingston and Andrew I. Cooper

A Pyrene-4, 5, 9, 10-Tetraone-Based Covalent Organic Framework Delivers High Specific Capacity as a Li-Ion Positive Electrode

Hui Gao, Alex R. Neale, Qiang Zhu, Mounib Bahri, Xue Wang, Haofan Yang, Yongjie Xu, Rob Clowes, Nigel D. Browning, Marc A. Little*, Laurence J. Hardwick, and Andrew I. Cooper

Organic Cage Inclusion Crystals Exhibiting Guest-enhanced Multiphoton Harvesting

Guo-Hong Ning, Peng Cui, Igor V Sazanovich, James T Pegg, Qiang Zhu, Zhongfu Pang, Rong-Jia Wei, Mike Towrie, Kim E Jelfs, Marc A Little*, and Andrew I Cooper

Integrated Covalent Organic Framework/Carbon Nanotube Composite as Li‐Ion Positive Electrode with Ultra‐High Rate Performance

Hui Gao, Qiang Zhu, Alex R Neale, Mounib Bahri, Xue Wang, Haofan Yang, Lunjie Liu, Rob Clowes, Nigel D Browning, Reiner Sebastian Sprick, Marc A Little, Laurence J Hardwick, and Andrew I Cooper

A Cubic 3D Covalent Organic Framework with nbo Topology

Xue Wang, Mounib Bahri, Zhiwei Fu, Marc A Little, Lunjie Liu, Hongjun Niu, Nigel D Browning, Samantha Y Chong, Linjiang Chen, John W Ward, and Andrew I Cooper

Creating Porosity in a Trianglimine Macrocycle by Heterochiral Pairing

Donglin He, Rob Clowes, Marc A. Little*, Ming Liu, and Andrew I Cooper

Inherent Ethyl Acetate Selectivity in a Trianglimine Molecular Solid

Donglin He, Chengxi Zhao, Linjiang Chen, Marc A. Little, Samantha Y Chong, Rob Clowes, Katherine McKie, Mark G Roper, Graeme M Day, Ming Liu, and Andrew I Cooper

Crystallography Companion Agent for High-Throughput Materials Discovery

Phillip M. Maffettone, Lars Banko, Peng Cui, Yury Lysogorskiy, Marc A. Little, Daniel Olds, Alfred Ludwig, and Andrew I. Cooper

Nano-assemblies of a Soluble Conjugated Organic Polymer and an Inorganic Semiconductor for Sacrificial Photocatalytic Hydrogen Production from Water

Haofan Yang,   Houari Amari,   Lunjie Liu,   Chengxi Zhao,   Hui Gao,   Ai He,   Nigel D. Browning,   Marc A. Little,   Reiner Sebastian Sprick, and Andrew I. Cooper.

3D Cage COFs: A Dynamic Three-Dimensional Covalent Organic Framework with High-Connectivity Organic Cage Nodes

Qiang Zhu, Xue Wang, Rob Clowes, Peng Cui, Linjiang Chen, Marc A. Little*, and Andrew I. Cooper

Crosslinked Polyimide and Reduced Graphene Oxide Composites as Long Cycle Life Positive Electrode for Lithium‐Ion Cells

Hui Gao, Bingbing Tian, Haofan Yang, Alex R. Neale, Marc A. Little, Reiner Sebastian Sprick, Laurence J. Hardwick, and Andrew I. Cooper

An Expandable Hydrogen-Bonded Organic Framework Characterised by Three-Dimensional Electron Diffraction

Peng Cui, Erik Svensson Grape, Peter R. Spackman, Yue Wu, Rob Clowes, Graeme M. Day, A. Ken Inge, Marc A. Little*, and Andrew I. Cooper

Inducing Social Self‐sorting in Organic Cages to Tune the Shape of the Internal Cavity

Valentina Abet, Filip T. Szczypiński, Marc A. Little, Valentina Santolini, Christopher D. Jones, Robert Evans, Craig Wilson, Xiaofeng Wu, Michael F. Thorne, Michael J. Bennison, Peng Cui, Andrew I. Cooper, Kim E. Jelfs, and Anna G. Slater

Organic Cage Dumbbells

Rebecca L. Greenaway, Valentina Santolini, Filip Szczypiński, Michael Bennison, Marc A. Little, Andrew Marsh, Kim E. Jelfs, and Andrew I. Cooper

Organic Heterojunctions for Direct Solar Fuel Generation

Reiner Sebastian Sprick, Marc A. Little*, and Andrew I. Cooper

Structure–activity Relationships in Well-defined Conjugated Oligomer Photocatalysts for Hydrogen Production from Water

Catherine M. Aitchison, Michael Sachs, Marc A. Little, Liam Wilbraham, Nick J. Brownbill, Christopher M. Kane, Frédéric Blanc, Martijn A. Zwijnenburg, James R. Durrant, Reiner Sebastian Sprick, and Andrew I. Cooper

Photocatalytic Proton Reduction by a Computationally Identified, Molecular Hydrogen-Bonded Framework

Catherine M. Aitchison, Christopher M. Kane, David P. McMahon, Peter Spackman, Angeles Pulido, Xiaoyan Wang, Liam Wilbraham, Linjiang Chen, Rob Clowes, Martijn A. Zwijnenburg, Reiner Sebastian Sprick, Marc A. Little, Graeme M. Day, and Andrew I. Cooper

The Chemistry of Porous Organic Molecular Materials

Marc A. Little*, and Andrew I. Cooper

Barely Porous Organic Cages for Hydrogen Isotope Separation

Ming Liu, Linda Zhang, Marc A. Little, Venkat Kapil, Michele Ceriotti, Siyuan Yang, Linjiang Chen, Lifeng Ding, Daniel L. Holden, Rafael Balderas-Xicohténcatl, Donglin He, Rob Clowes, Samantha Y. Chong, Gisela Schütz, Michael Hirscher, and Andrew I. Cooper.

Mining Predicted Crystal Structure Landscapes with High Throughput Crystallisation: Old Molecules, New Insights

Peng Cui, David P. McMahon, Peter Spackman, Ben M. Alston, Marc A. Little, Graeme Day, and Andrew I Cooper

From Concept to Crystals via Prediction: Multi-Component Organic Cage Pots by Social Self-Sorting

Rebecca L. Greenaway, Valentina Santolini, Angeles Pulido, Marc A. Little, Ben M. Alston, Michael Briggs, Graeme Day, Andrew I. Cooper, and Kim Jelfs

Synthesis of a Large, Shape-Flexible, Solvatomorphic Porous Organic Cage

Baiyang Teng, Marc A. Little*, Tom Hasell, Samantha Y. Chong, Kim E. Jelfs, Michael E. Briggs, and Andrew I. Cooper

Control of Conformation in α-Helix Mimicking Aromatic Oligoamide Foldamers Through Interactions Between Adjacent Side-chains

Irene Arrata, Claire M. Grison, Heather M. Coubrough, Panchami Prabhakaran, Marc A. Little, Darren C. Tomlinson, Michael E. Webb, and Andrew J. Wilson

Sulfone-containing Covalent Organic Frameworks for Photocatalytic Hydrogen Evolution from Water

Xiaoyan Wang, Linjiang Chen, Samantha Y. Chong, Marc A. Little, Yongzhen Wu, Wei-Hong Zhu, Rob Clowes, Yong Yan, Martijn A. Zwijnenburg, Reiner Sebastian Sprick, and Andrew I. Cooper

Computational Modelling of Solvent Effects in a Prolific Solvatomorphic Porous Organic Cage

David P. McMahon, Andrew Stephenson, Samantha Y. Chong, Marc A. Little, James T. A. Jones, Andrew I. Cooper, and Graeme M. Day

High-throughput Discovery of Organic Cages and Catenanes Using Computational Screening Fused with Robotic Synthesis

Rebecca L. Greenaway, Valentina Santolini, Michael J. Bennison, Ben M. Alston, Chloe J. Pugh, Marc A. Little, Marcin Miklitz, Edward G. B. Eden-Rump, Rob Clowes, Anika Shakil, Helen J. Cuthbertson, Helen Armstrong, Michael E. Briggs, Kim E. Jelfs, and Andrew I. Cooper

Near-Ideal Xylene Selectivity in Adaptive Molecular Pillar[n]arene Crystals

Kecheng Jie, Ming Liu, Yujuan Zhou, Marc A. Little, Angeles Pulido, Samantha Y. Chong, Andrew Stephenson, Ashlea R. Hughes, Fumiyasu Sakakibara, Tomoki Ogoshi, Frédéric Blanc, Graeme M. Day, Feihe Huang, and Andrew I. Cooper

Cage Doubling: Solvent-Mediated Re-equilibration of a [3+ 6] Prismatic Organic Cage to a Large [6+ 12] Truncated Tetrahedron.

Chloe J. Pugh, Valentina Santolini, Rebecca L. Greenaway, Marc A. Little, Michael E Briggs, Kim E. Jelfs, and Andrew I. Cooper

A Solution-processable Dissymmetric Porous Organic Cage

Anna G. Slater, Marc A. Little, Michael E. Briggs, Kim E. Jelfs, and Andrew I. Cooper

Computationally-Guided Synthetic Control over Pore Size in Isostructural Porous Organic Cages

Anna G. Slater, Paul S. Reiss, Angeles Pulido, Marc A. Little, Daniel L. Holden, Linjiang Chen, Samantha Y. Chong, Ben M. Alston, Rob Clowes, Maciej Haranczyk, Michael E. Briggs, Tom Hasell, Graeme M. Day, and Andrew I. Cooper

Modular Assembly of Porous Organic Cage Crystals: Isoreticular Quasiracemates and Ternary Co-crystal

Srinu Tothadi, Marc A. Little, Tom Hasell, Michael E. Briggs, Samantha Y. Chong, Ming Liu, and Andrew I. Cooper.

Chirality as a Tool for Function in Porous Organic Cages

Tom Hasell, Marc A. Little, Samantha Y. Chong, Marc Schmidtmann, Michael E. Briggs, Valentina Santolini, Kim E. Jelfs, and Andrew I. Cooper.

Functional Materials Discovery using Energy-Structure-Function Maps

Angeles Pulido, Linjiang Chen, Tomasz Kaczorowski, Daniel Holden, Marc A. Little, Samantha Y Chong, Benjamin J Slater, David P McMahon, Baltasar Bonillo, Chloe J Stackhouse, Andrew Stephenson, Christopher M Kane, Rob Clowes, Tom Hasell, Andrew I Cooper, and Graeme M Day

Styrene Purification by Guest-Induced Restructuring of Pillar[6]arene

Kecheng Jie, Ming Liu, Yujuan Zhou, Marc A. Little, Satyanarayana Bonakala, Samantha Y. Chong, Andrew Stephenson, Linjiang Chen, Feihe Huang, and Andrew I. Cooper

Reticular Synthesis of Porous Molecular 1-Dimensional Nanotubes and 3-Dimensional Networks

Anna G. Slater, Marc A. Little, Angeles Pulido, Samantha Y. Chong, Daniel Holden, Linjiang Chen, Callum Morgan, Xiofeng Wu, George Cheng, Rob Clowes, Michael E. Briggs, Tom Hasell, Kim E. Jelfs, Graeme M. Day, and Andrew I. Cooper

Three-dimensional Protonic Conductivity in Porous Organic Cage Solids

Ming Liu, Linjiang Chen, Scott Lewis, Samantha Y. Chong, Marc A. Little, Tom Hasell, Iain M. Aldous, Craig M. Brown, Martin W. Smith, Carole A. Morrison, Laurence J. Hardwick, and Andrew I. Cooper

Periphery-Functionalised Porous Organic Cages

Paul S. Reiss, Marc A. Little, Valentina Santolini, Samantha Y. Chong,Tom Hasell, Kim E. Jelfs, Michael E. Briggs, and Andrew I. Cooper.

A Unified Treatment of the Relationship between Ligand Substituents and Spin State in a Family of Iron (II) Complexes

Laurence J. Kershaw Cook, Rafal Kulmaczewski, Rufeida Mohammed, Stephen Dudley, Simon A. Barrett, Marc A. Little, Robert J. Deeth, and Malcolm A. Halcrow

Porous Organic Cages for Sulfur Hexafluoride Separation

Tom Hasell, Marcin Miklitz, Andrew Stephenson, Marc A. Little, Samantha Y. Chong, Rob Clowes, Linjiang Chen, Daniel Holden, Gareth A. Tribello, Kim E. Jelfs, and Andrew I. Cooper

Dynamic Flow Synthesis of Porous Organic Cages

Michael E. Briggs, Anna G. Slater, Neil Lunt, Shan Jiang, Marc A. Little, Rebecca L. Greenaway, Tom Hasell, Claudio Battilocchio, Steven V. Ley, and Andrew I. Cooper

Trapping Virtual Pores by Crystal Retro-engineering

Marc A. Little, Michael E. Briggs, James T. A. Jones, Marc Schmidtmann, Tom Hasell, Samantha Y. Chong, Kim E. Jelfs, Linjiang Chen, and Andrew I. Cooper

*Highlighted in news and views ‘Organic cage crystals: Supramolecular joinery’ by Leonard J. Barbour, Nature Chemistry, 2015, 7, 97–99.

Hydrogels Formed From Fmoc Amino Acids

Emily R. Draper, Kyle L. Morris, Marc A. Little, Jaclyn Raeburn, Catherine Colquhoun, Emily R. Cross, Tom O. McDonald, Louise C. Serpell, and Dave J. Adams

The Effect of Solvent Choice on the Gelation and Final Hydrogel Properties of Fmoc–diphenylalanine

Jaclyn Raeburn, Cristina Mendoza-Cuenca, Beatrice N Cattoz, Marc A Little, Ann E Terry, Andre Zamith Cardoso, Peter C Griffiths, and Dave J Adams

Separation of Rare Gases and Chiral Molecules by Selective Binding in Porous Organic Cages

Linjiang Chen, Paul S. Reiss, Samantha Y. Chong, Daniel Holden, Kim E. Jelfs, Tom Hasell, Marc A. Little, Adam Kewley, Michael E. Briggs, Andrew Stephenson, K. Mark Thomas, Jayne A. Armstrong, Jon Bell, Jose Busto, Raymond Noel, Jian Liu, Denis M. Strachan, Praveen K. Thallapally, and Andrew I Cooper

Acid-and Base-stable Porous Organic Cages: Shape Persistence and pH Stability via Post-synthetic ‘Tying’ of a Flexible Amine Cage

Ming Liu, Marc A. Little, Kim E. Jelfs, James T. A. Jones, Marc Schmidtmann, Samantha Y. Chong, Tom Hasell, and Andrew I. Cooper

Guest Control of Structure in Porous Organic Cages

Marc A. Little, Samantha Y. Chong, Marc Schmidtmann, Tom Hasell, and Andrew I. Cooper

Iron(II) Complexes of 2,6-di(1-alkylpyrazol-3-yl)pyridine derivatives – The influence of Distal Substituents on The Spin State of The Iron Centre

Thomas D. Roberts. Marc A. Little, Laurence J. Kershaw Cook, Simon A. Barrett, Floriana Tuna, Malcolm A. Halcrow

Complex Thermal Expansion Properties in a Molecular Honeycomb Lattice

Jonathan J. Loughrey, Tim P. Comyn, David C. Apperley, Marc A. Little, and Malcolm A Halcrow

Predicted Crystal Energy Landscapes of Porous Organic Cages

Edward O. Pyzer-Knapp, Hugh P. G. Thompson, Florian Schiffmann, Kim E. Jelfs, Samantha Y. Chong, Marc A. Little, Andrew I. Cooper, and Graeme M. Day

Hexasulfanyl Analogues of Cyclotriveratrylene

Marc A. Little, Jonathan J. Loughrey, Amedeo Santoro, Malcolm A. Halcrow, and Michaele J. Hardie

Controlling the Crystallisation of Porous Organic Cages: Molecular Analogs of Isoreticular Frameworks Using Shape-specific Directing Solvents

Tom Hasell, Jamie L. Culshaw, Samantha Y. Chong, Marc Schmidtmann, Marc A. Little, Kim E. Jelfs, Edward O. Pyzer-Knapp, Hilary Shepherd, Dave J. Adam, Graeme M. Day, and Andrew I. Cooper.

Iron (ii) Complexes of 2, 6-di (1 H-pyrazol-3-yl)-pyridine Derivatives with Hydrogen Bonding and Sterically Bulky Substituents

Thomas D. Roberts, Marc A. Little, Laurence J. Kershaw Cook, and Malcolm A. Halcrow

Electrochemical Synthesis of a Tetradentate Copper N-Heterocyclic Carbene Calix[4]arene and Its Transmetalation to Palladium: Activity of the Palladium Complex in Suzuki-Miyaura Cross-Coupling

Emma K. Bullough, Colin A. Kilner, Marc A. Little, and Charlotte E. Willans 

A Bis(disulfide)-linked Offset Cryptophane

Marc A. Little, Malcolm A. Halcrow, and Michaele J. Hardie

Isostructural Salts of the Same Complex Showing Contrasting Thermal Spin-crossover Mediated by Multiple Phase Changes

Thomas D. Roberts, Marc A. Little, Floriana Tuna, Colin A. Kilner, and Malcolm A Halcrow

Synthesis and Methane Binding Properties of Disulfide-linked Cryptophane-0.0.0

Marc A. Little, Jessica Donkin, Julie Fisher, Malcolm A. Halcrow, Jordan Loder, and Michaele J. Hardie

Rhodium-catalysed Isomerisation/formal 1, 3-dipolar Cycloaddition Cascades to Fused-ring Heterocycles

Ryan M. Gorman, Marc A. Little, James A. Morris, and Visuvanathar Sridharan

Tetrakis(methylimidazole) and Tetrakis(methylimidazolium) Calix [4] Arenes: Competitive Anion Binding and Deprotonation

Emma K. Bullough, Colin A. Kilner, Marc A. Little, and Charlotte E. Willans 

Simple and Versatile Selective Synthesis of Neutral and Cationic Copper (i) N-heterocyclic Carbene Complexes Using an Electrochemical Procedure

Benjamin R. M. Lake, Emma K. Bullough, Thomas J. Williams, Adrian C. Whitwood, Marc A. Little, and Charlotte E. Willans

New Coordination Polymers with Extended Arm Cyclotriguaiacyclene Ligands: 1D chains, and Interpenetrating or Polycatenating 2D (42.62)(4.62)2 Networks

Marc A. Little, Tanya K. Ronson, and Michaele J. Hardie

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